Usos de las tabletas de hidrobromuro de vortioxetina
Hay cuatro especificaciones para la vortioxetina: 5 mg, 10 mg, 15 mg, 20 mg. El hidrobromuro de vortioxetina se considera un nuevo fármaco antidepresivo multimodelo. Los estudios in vitro han demostrado que puede antagonizar los receptores 5-HT3, 5-HT7 y 5-HT1D, activar los receptores 5-HT1A y activar parcialmente el receptor 5- HT1B e inhibir el transporte de 5-HT. El hidrobromuro deortioxetina es un nuevo tipo de bisarilsulfanilamina antidepresivo desarrollado conjuntamente por Takeda Japan y Lingbei, Dinamarca. Se utiliza en el tratamiento de la depresión y la ansiedad.
| Items | Standards | Results |
| Appearance | White to light-yellow solid | Complies |
| Identification | By IR | Complies |
| By HPLC | Complies | |
| Loss on Drying | ≤0.50% | 0.30% |
| Heavy Metals | ≤20ppm | Complies |
| Residue on Ignition | ≤0.10% | 0.04% |
| Related Substances | Maximum single impurity: ≤0.10% | 0.05% |
| Total Impurities: ≤1.00% | 0.08% | |
|
Assay (HPLC basis on drying) |
98.0%~102.0% | 99.93% |
| Reference Standard | In-house Standard | |
| Conclusion | The product complied to In-house standard. | |
| Storage | Preserve in tight,light-resistant containers in a cool place | |
PRODUCTOS POR GRUPO : Vortioxetine Hydrobromide
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